ea0034p270 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2014
Thomas Nihal
, Mahesh D M
, Chapla Aaron
, Paul Johan
, Shwetha N
, Christina Flory
, Asha H S
Introduction: Genetic predisposition with environmental factors plays a significant role in the development of type 2 diabetes mellitus. Among the diabetogenic genes, the transcription factor 7-like 2 (TCF7L2), a member of the Wnt signalling pathway remains the strongest genetic determinant of type 2 diabetes risk in humans. Our aim was to investigate whether TCF7L2 variants that have previously been associated with type2 diabetes would also confer risk for gestational diabete...